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Cannabinoids

by | Oct 28, 2021 | Cannabinoids | 0 comments

 

Cannabinoids are the chemical compounds found within the cannabis plant. Don’t be intimidated by the word “chemical”: the chemicals found in the cannabis plant are natural and largely have no adverse effects.

 

These compounds found in cannabis trigger chemical reactions inside the human body by attaching themselves to receptors in the brain and the central nervous system. There are hundreds of cannabinoids, but the below list details the most common.

 

Cannabis and the ECS

All cannabinoids are able to work with the human body’s endocannabinoid system (ECS) by attaching themselves to receptors and altering the chemical structure. The ECS controls the homeostasis of a number of internal systems, so it’s possible for cannabinoids to provide therapeutic results to different parts of the body.  For more information on the ECS, check out our blog post with more details.

 

Cannabinoids are extracted from the Cannabis plant

 

This article takes a closer look at plant cannabinoids, and how its effect on the central nervous system can help treat chronic pain and other ailments.

 

Plant Cannabinoids in Cannabis

Cannabis is well known for producing the cannabinoid tetrahydrocannabinol (THC). Tetrahydrocannabinol (THC) is known for its psychoactive effects. However, this is not indicative of the overall effects of cannabis. The other types of cannabinoids found in the cannabis plant do not have the psychoactive effects like THC.

 

Types of Cannabinoids

More recently one of the other cannabinoids it produces called cannabidiol (CBD) has been getting more recognition as well.

However cannabis also produces more than one hundred other cannabinoids, albeit in much smaller quantities. Because the level of these cannabinoids is so much lower than those of THC and CBD, it’s difficult for researchers to know exactly how many other cannabinoids exist in the cannabis plant and their effect on the central nervous system.

Nevertheless, researchers have been able to gather data on the handful of cannabinoids that are present in more substantial amounts. Let’s start with the some of the most well-known types of cannabinoids.

 

Tetrahydrocannabinol (THC)

Most people know tetrahydrocannabinol (THC) for its association with marijuana and its ability to make the user experience a euphoria throughout the body.

THC also has the ability to create a wide range of short-term effects when consumed. Some people may feel the effects more than others, some not at all, and some may feel the effects amplified.

Common short-term effects of THC include elation, relaxation, sedation, pain relief, energy, dry mouth, laughter, and anxiety.

Ultimately it all comes down to a person’s body chemistry, but different strains and concentrations of THC also play a role in how someone may feel after THC is consumed. 

 

CBD (Cannabidiol)

For those looking for the benefits of THC without the high, there’s CBD.

This compound has been taking the market by storm over the last few years and shows no signs of slowing. Researchers have just begun studying all the benefits of CBD, but the results are already promising. 

CBD may help with a number of things including fighting inflammation, anxiety and stress, chronic and acute pain, workout recovery, mental focus, sleep aide, healing injuries, Parkinson’s Disease, Bruxism, dementia, cancer, alcoholism, epilepsy, and opioid addiction.

It may even help your pets with anxiety and pain!

 

CBG (Cannabigerol)

CBG, while not present in large quantities in most strains, is still one of the most important compounds because it is the “mother” cannabinoid that all other cannabinoids are synthesized from.

It is only measurable at around 1% in most cannabis, so CBG would be what’s considered a minor cannabinoid however it still offers exciting potential for therapeutic benefits.

Some breeders are even experimenting with CBG and genetic manipulation in order to obtain strains that produce more CBG. 

Like CBD, CBG has many potential uses which include anti-inflammation, pain relief, reducing nausea, calming anxiety, treating irritable bowel syndrome, and slowing the proliferation of cancer cells.

 

CBC (Cannabichromene)

CBC is considered one of the “big six” of cannabinoids present in cannabis plants.

It was first discovered over 50 years ago and has been researched for its medicinal benefits since.

While it’s not as popular as CBD or THC, it still shows a lot of promise for potential benefits for a range of issues.

CBC, like all other cannabinoids except THC, produces no mind altering effects or any sort of “high” feeling. It does, however, work extremely well with other cannabinoids.

 

CBN (Cannabinol)

Like most of the other cannabinoids, cannabinol is non-intoxicating, but this compound is actually created by the process of THC aging. This means CBN is generally found in larger quantities in older cannabis flowers that contain THC.

Some users actually seek out older cannabis in order to get the additional benefits of larger quantities of CBN in the aged plant. 

Its uses may include pain relief, slowing bacterial growth, helping sleep, and treating muscle spasms.

CBGV (Cannabigerivarin)

Cannabigerivarin is a cannabinoid acid that originates from CBG.

CBGV is found in small amounts in certain cannabis strains and is activated by exposure to heat or light.

CBGV plays an important role in the consumption of CBD, where it helps the body metabolize the compound.

Overall, it would be considered an enhancer for the cannabinoids entering the body, ultimately increasing their effectiveness. 

 

THCV (Tetrahydrocannabivarin)

THCV is similar to THC in molecular structure and, like THC, does have psychoactive properties. Its overall effects are different from those of THC, however.

THCV generally has stronger psychoactive effects than THC alone and for a shorter period of time.

Research has shown that THCV can inhibit some effects of THC while enhancing others.

 

CBDV (Cannabidivarin)

Cannabidivarin is structurally similar to CBD and like CBD it has no intoxicating effect on the user.

Typically cannabis strains higher in CBD will also be higher in CBDV.

Most of the research around CBDV has been focused on its effect on seizures with similar findings as those studying CBD as an anticonvulsant.

 

CBCV (Cannabichromevarin)

CBCV exists at lower levels in cannabis than THC and CBD and is more closely related to CBC. Because of its similarity to CBC it works much in the same way with many of the same benefits.

Like other cannabinoids, research is still very new and limited on therapeutic benefits, but it is ongoing and researchers are continuing to dig into the possibilities of CBCV.

 

Cannabinoid Receptors

Endocannabinoid receptors are found on the surface of cells and are used to monitor conditions outside the cell and transmit any information about changes happening within the environment surrounding it.

If a large enough change is reported, the ECS will receive the message communicated by the receptors and initiate the proper response to balance the system. Endocannabinoids are able to bind to either of the two main receptors, but the result will depend on where the receptor is located and which endocannabinoid it binds to.

 

Chronic Pain

One of the most exciting effects of cannabis includes its abilities to treat chronic pain. In fact, studies show that the cannabis plant may have many positive effects on the nervous system, and may treat pain.

 

Woman taking Cannabinoid (CBD) drops

 

For more information on cannabis and it’s affect on pain, check out our CBD for Pain blog post.

 

Trying Cannabis Products

If you are just starting out with trying a cannabinoid, we recommend CBD. CBD is the most widely available and trusted. You’ll also want to discuss CBD with your doctor, because cannabinoids are not right for everyone.

It’s important to go with a manufacturer that does third party laboratory testing, because many products are mislabeled. All of MojaveRx’s products are produced to the highest standard and undergo third party laboratory testing. If you have any questions about the right CBD product for you, contact MojaveRx today.

 

Conclusion

The effects of cannabis are still being studied. What we currently understand about the cannabis plant’s effects throughout the body show great promise in treating pain, anxiety, and much more.

The coming years will surely show exciting developments in the cannabis field of research.