Is Cannabis Safe During Pregnancy

by | Apr 5, 2021 | Pregnancy | 0 comments

Marijuana products are becoming more and more popular. Many believe in their magical healing properties. Due to the gradual legalization of cannabis in different countries and a fast increase in their safety perception, more and more people use them as a catch-all remedy for diverse conditions.

Many women use CBD products even during pregnancy to curb morning sickness and nausea. Proof of this is a government study of 2019, which says marijuana use among expectant mothers has more than doubled since 2002.

Pregnancy can be an especially stressful time in a person’s life. A lot of the common issues pregnant people experience would otherwise be eased by the use of cannabis, like increased anxiety levels, nausea, and appetite issues.

But is it safe for the expectant parent to use cannabis during pregnancy? What should one know about maternal cannabinoid exposure? What about after the baby is born? Is the new parent experiencing heightened anxiety, depression, or pain? And is it okay for them to then take cannabis?



First, let’s discuss what makes cannabis products so effective in a wide variety of issues people may suffer from. It happens at a molecular level and within the Endocannabinoid System (ECS) of the human body. The ECS is the system in control of homeostasis within the body. It’s where the body senses and corrects any type of disturbance that happens internally. The ECS functions use three primary elements called endocannabinoids, receptors, and enzymes.

Endocannabinoids are naturally occurring chemical compounds found within the human body. These compounds are very similar to the chemical compounds found in cannabis, otherwise known as cannabinoids. Since the two compounds are so molecularly similar, cannabinoids can easily attach themselves to endocannabinoid receptors.

The receptors within the endocannabinoid system are found on the surface of cells throughout the body. When endocannabinoid (or cannabinoid) compounds attach themselves to the receptors, it allows them to communicate with different systems, helping the ECS maintain homeostasis. The receptors and compounds stay attached to each other until enzymes are introduced to break the connection.

Enzymes within the ECS are introduced after the receptor and endocannabinoid have worked together to achieve the desired level of stabilization in a specific system. Once the flux in homeostasis has been corrected, the enzymes attach to the endocannabinoids and break them down.

Because the body’s natural endocannabinoids and the cannabinoids from a cannabis plant are so similar, cannabis products like CBD and other cannabinoids have an opportunity to interact with the human body in a special way. CBD can attach itself to the ECS receptors, effectively dampening or blocking some signals they are sending or even using itself as a barrier between the receptor and the enzyme, protecting the endocannabinoid attached to it.



A recent study conducted in California found that nearly 11% of women reported using cannabis while they were pregnant. Cannabis is legal in California, and the study reports that the number of women using cannabis while pregnant increased from 6% when it was last surveyed before legalization. It should be noted, however, that the study does not designate differences in strain or type of cannabis, including THC levels [1]. This particular study is just one of many.

However, like the others, the information is somewhat limited as it does not include data on CBD use. It also does not include information about whether the expectant mothers are also using substances like nicotine or caffeine. Why is that aspect important? Well, without that additional information, it’s difficult to determine whether any conditions after birth are present due to cannabis or other factors, such as those substances.

Overall, studies on the effects of cannabis use during pregnancy have provided inconsistent results. Much of this comes from the fact that timing of use during pregnancy may play a large part in determining what developmental effects are seen. For instance, the cannabinoid type I, or CB1, receptors that THC would normally activate to feel a certain level of intoxication is not present in the developing fetus until around 19 weeks.

However, in studies performed on monkeys, researchers found that THC quickly passed through the placenta and was easily detected in fetal blood within just 15 minutes of the mother ingesting marijuana [2]. The ability of the THC to pass into the fetus’ bloodstream, however, does not mean the fetus actually becomes intoxicated. In fact, it’s not until the third trimester that a fetal brain has the proper structures in place for that effect to take place, and even at that point, the experience would be very different than what we know [3].

Regardless, CB1 receptors and all the rest of the endocannabinoid system still plays a huge role in brain development. These receptors are responsible for influencing how brain cells develop, where they go, which ones to connect to, how to connect, and what to look like. So if the development of these cells is interrupted by THC binding itself to the receptor, it could be disruptive and lead to issues like lower birth weight, premature labor, and higher odds of needing to be admitted to neonatal intensive care [4].



While the research is still ongoing on what effects cannabis truly does have on a developing fetus, scientists are beginning to see that whatever effects of cannabis are present, they are heightened even further by the addition of other substances like tobacco and alcohol.

One study suggests that pregnant mothers combining tobacco and cannabis would be more likely to see their baby have a difficult time with the ability to self-soothe when compared to infants from mothers who only used tobacco [5]. This particular effect is more common in baby girls. However, another study concluded that cannabis combined with tobacco use led to dysfunction in baby boys that impaired their ability to regulate their stress [6].

While there haven’t been studies yet, it is also possible that other medications for anxiety, nausea, and sleep that expecting mothers may be taking could also bring higher odds of developmental issues when combined with cannabis products. While there is no definitive proof yet, pregnant women should be aware of the potential risks.



Multiple studies have found that THC harms brain development, meaning pregnant women should avoid cannabis products like marijuana. Specifically, the regions of the brain associated with impulse control, executive functioning, emotional development, and reward processing are especially susceptible to damage from the THC cannabinoid if a fetus’ brain is exposed to it [7].

Even older children may feel the effects of cannabis if they are exposed to it while in the womb. A report found that even 10-year-old children had higher levels of depression if their mothers took high doses of CBD during even the first trimester [8].

There haven’t been studies on CBD’s effects on a developing fetus’s brain. However, CBD has more than 65 targets in the brain and body of a fetus and uses the endocannabinoid system to activate its results, so scientists are unsure what its long-term consequences could be. There is no clear evidence that it could harm a fetal brain, but there is also nothing proving its safety.



Even after birth, a baby can still be affected by cannabis, either through secondhand smoke or breastmilk. One study found that THC and other metabolites were found in adults in trace amounts after being exposed to secondhand marijuana smoke. Lower trace levels such as these wouldn’t be likely to impact a child in any detrimental way.

However, repeated exposure to that secondhand marijuana smoke has the potential to build up over time due to the fat-soluble properties of THC and other cannabinoids [9].

Cannabinoids easily transfer from breast milk to an infant, with THC being detected in breast milk for up to 6 days after consumption [10]. However, some studies have shown there was no transfer at all. Right now, it is unclear what factors lead to the transfer of THC in only some of the cases, but it’s still best to be more cautious than not.

Researchers have also found variability in the proportion of THC that gets transferred to the infant in breast milk, with the numbers ranging from as little as 0.4% to as much as 8.7% [11]. There are no obvious predictors to explain why different people fall into different ranges, but studies do estimate that infant exposure is about 1,000 times lower than the mother’s would be. It remains unclear if that is enough to damage the child’s brain development, however [12].

While so much of the research is still ongoing and overall fairly inconclusive, one thing is for sure: there is evidence that suggests cannabis products may impact the development of a fetus, so expectant mothers should speak to the doctor and always err on the side of caution by avoiding cannabis products while they are pregnant or breastfeeding. Cannabis products like marijuana and CBD should have a permanent place in the medicine cabinet, but during certain life events, it’s safer to let them sit unused to prevent possible risks.


The Bottom Line

Cannabis use during pregnancy is not a rare occasion due to its potential properties that may decrease morning sickness, nausea, anxiety levels, etc. But is cannabis safe during such an important period?

While there is no absolute evidence yet, pregnant women should be aware of the potential risks. However, numerous studies have proved that the major compound of cannabis, THC, harms brain development. The regions of the brain associated with impulse control, executive functioning, emotional development, and reward processing are especially susceptible.

What is more, cannabinoids easily transfer from breast milk to an infant, with THC being detected in breast milk for up to 6 days after consumption. All these mean only one thing: pregnant women should avoid using cannabis.


FAQs About Cannabis Use During Pregnancy


Is Cannabis Safe During Pregnancy?

Cannabis use during pregnancy is not safe and may even be harmful to your baby’s health due to the content of THC (tetrahydrocannabinol.) It passes through your system to the newborn and may harm your child’s development.


What Benefits Can CBD Have?

Among the currently claimed benefits of CBD are pain relief (including chronic pain associated with fibromyalgia, nervous system disorders, and cancer), reduced anxiety, improved sleep, and nausea relief. Since CBD is linked to serotonin receptors, it helps regulate your mood and overall sense of well-being.


Can You Use CBD While Pregnant?

CBD and pregnancy are highly discussed topics. CBD, which is found in marijuana and hemp plants, is considered safe due to the absence of THC (tetrahydrocannabinol) responsible for giving you the intoxicating “high.”

FDA (Food and Drug Administration) continues its study of the data on the potentially harmful effects of CBD-containing products during pregnancy and breastfeeding.

The FDA strongly advises avoiding using CBD and THC or any form of marijuana during this particular period. There may be serious risks due to the absence of comprehensive research and the number of unanswered questions concerning the science, quality, and safety of products containing CBD.

The FDA plans to continue researching whether CBD in human milk harms the baby while breastfeeding or the mother’s milk production.


Is CBD Oil Safe During Pregnancy?

Pregnant women turn to CBD oil because it helps with the short-term relief of such unpleasant symptoms of the difficult period as pain, nausea, stress, morning sickness, etc.

Still, there are no unambiguous studies that can confirm whether CBD during pregnancy is beneficial or not. If you feel unable to resist its use, please ensure you are dealing with exclusively natural and reliable products. And the most important thing: consult with your doctor before making such decisions.


What Are the Effects of CBD During Pregnancy And Breastfeeding?

As previously mentioned, there are no clear answers due to the lack of thorough research and the number of unanswered questions concerning the effects of CBD on the developing fetus, breastfed baby, or pregnant mother.

However, given what we currently know, there is a reason for concern. Among the possible risks are the effect on a baby’s brain development in the womb and the high chances of stillbirth or premature birth. Not only do experts think THC can pass to an infant through breast milk, but it can also happen with CBD as well.

Also, there are reports that CBD potentially contains other contaminants such as heavy metals, pesticides, fungi, and bacteria. These cannot but affect both mother and fetus.



The statements expressed on this website are purely opinion of the author and not factual. These statements have not been evaluated by the Food and Drug Administration. Any products referenced on this website are not intended to diagnose, treat, cure, or prevent any disease. It’s highly suggested to consult with your medical professional prior to any use of the products referenced on this website. This website and author specifically disclaim any liability in connection with the products contained on the website.


Michael Lagnese

Michael Lagnese is the co-founder and CEO of Mojave Rx - a consumer-focused CBD brand specializing in creating high potency products to support athletic performance, physical rehabilitation, and muscle recovery. Outside of his professional endeavors, Michael is also passionate about his personal growth journey. Exercise, meditation, reading, journaling, and continued education are all of the utmost importance and, in his opinion, the key to becoming a more effective leader. Above all, Michael is passionate about making a positive difference in people’s lives, and through Mojave Rx and their top-quality products, he hopes to continue on this journey for many years to come.